Author/Authors :
Shooshtarizadeh, P Endocrinology and Metabolism Research Centre (EMRC) - Shariati Hospital - School of Medicine - Tehran University of Medical Sciences - Tehran, Iran , Lankarani, M Endocrinology and Metabolism Research Centre (EMRC) - Shariati Hospital - School of Medicine - Tehran University of Medical Sciences - Tehran, Iran , Soleimanpour, B Endocrinology and Metabolism Research Centre (EMRC) - Shariati Hospital - School of Medicine - Tehran University of Medical Sciences - Tehran, Iran , Aghakhani, S Endocrinology and Metabolism Research Centre (EMRC) - Shariati Hospital - School of Medicine - Tehran University of Medical Sciences - Tehran, Iran , Mahmoodzadeh, H Department of Surgery - Shariati Hospital - School of Medicine - Tehran University of Medical Sciences - Tehran, Iran , Poorpezeshk, N Department of Surgery - Shariati Hospital - School of Medicine - Tehran University of Medical Sciences - Tehran, Iran , Haghpanah, V Endocrinology and Metabolism Research Centre (EMRC) - Shariati Hospital - School of Medicine - Tehran University of Medical Sciences - Tehran, Iran , Heshmat, R Department of Epidemiology and Biostatistics - Public School of Health - Tehran University of Medical Sciences - Tehran, Iran
Abstract :
Postsurgical hypothyroidism and its incidence has not been fully investigated. In this
study, the incidence of hypothyroidism and its possible risk factors at Shariati Hospital was assessed.
One hundred and two patients with benign thyroid diseases, who had undergone thyroidectomy, were
investigated with regards to thyroid function profile during period of one year after the operation every
three months with post-operative sample as the baseline. Hypothyroidism was developed in 36 patients
(35.2%) on average 5 ± 3.2 months after surgery. Factors such as increased age, operation type,
histopathologic type, underlying disease, lymphocytic infiltration and use of levothyroxine before
surgery were associated with the increased incidence of hypothyroidism. It seems that use of indicators
such as Graves' disease and lymphocytic infiltration in pathologic specimens should be helpful in
projecting the potential occurrence of hypothyroidism in patients undergoing thyroidectomy.
Keywords :
relative risk , risk factors , hypothyroidism , Thyroidectomy
