Author/Authors :
Un, Bulent Department of Anesthesiology and Reanimation - School of Medicine - Osmangazi University, Eskisehir, Turkey , Ceyhan, Dilek Department of Anesthesiology and Reanimation - School of Medicine - Osmangazi University, Eskisehir, Turkey , Yelken, Birgul Department of Anesthesiology and Reanimation - School of Medicine - Osmangazi University, Eskisehir, Turkey
Abstract :
BACKGROUND: Etomidate frequently leads to myoclonic jerks during anesthetic induction. This study aimed to detect if
pretreatment with magnesium decreases myoclonus incidence.
METHODS: A hundred ASA (the American Society of Anesthesiologists) I-II patients were included and randomized
into 2 groups. Three minutes before etomidate induction of anesthesia (by 0.3 mg/kg intravenous etomidate) , Group M
received 2.48 mmol (60 mg) intravenous magnesium sulphate and Group P received equal volume of intravenous saline.
Myoclonus was evaluated as "present/absent".
RESULTS: The rate of myoclonus was significantly lower in Group M than in Group P (p < 0.01). Hemodynamic parameters
revealed no significant difference between the two groups.
