Author/Authors :
Dana Siadat, Zahra Department of Community Medicine - School of Medicine, Isfahan University of Medical Sciences, Isfahan , Shariat, AmirSina Student of Medicine - School of Medicine and Student Research Committee, Isfahan University of Medical Sciences, Isfahan , Kiani, Keyvan Student of Medicine - School of Medicine and Student Research Committee, Isfahan University of Medical Sciences, Isfahan , Sadeghi, Masoumeh Cardiac Rehabilitation Research Center - Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan , Farajzadegan, Ziba Department of Community Medicine - School of Medicine, Isfahan University of Medical Sciences, Isfahan , Kheirmand, Maryam Department of Community Medicine - School of Medicine, Isfahan University of Medical Sciences, Isfaha
Abstract :
Several factors such as hyperlipidemia, diabetes and hypertension have a determining role in cardiovascular disease.
In recent years, the effect of vitamin D deficiency on cardiovascular disease has been emphasized. This study compares vitamin
D deficiency in coronary heart disease patients with the control group. METHODS: In a cross-sectional study, 25-
hydroxycholecalciferol level was compared in 119 individuals including 57 people with confirmed coronary heart disease and 62
healthy people. 25-hydroxyvitamin D [25(OH)D] was assessed using standard protocol. The level of 25(OH)D under 20 ng/dl was
determined as cutoff point. RESULTS: The calculated odds ratio was 3.9 (95% confidence interval 2.6-5.5). Vitamin D deficiency
significantly different between patients and the control group (p = 0.01). Of 37 (31%) individuals having vitamin D deficiency, 36
(97.3%) had coronary artery disease and from 57 patients with coronary artery disease 36 (63.2%) had vitamin D deficiency.
CONCLUSIONS: Vitamin D deficiency is a relatively common disorder. Risk of cardiovascular disease in people with vitamin D
deficiency is almost four times of those with normal levels of
