Other language title :
ﺑﺮرﺳﻲ ﺑﺎﻟﻴﻨﻲ ﺗﺎﺑﺶ ﻟﻴﺰر ﺟﻠﺪي ﺧﻮﻧﻲ ﺑﺮ ﺗﻐﻴﻴﺮات ﻫﻤﻮدﻳﻨﺎﻣﻴﻜﻲ ﺳﮓﻫﺎي ﺑﻴﻬﻮش
Title of article :
Cumulative Clinical Evaluation of Transcutaneous Blood Laser Irradiation on Hemodynamic Changes in Anesthesia of Dogs
Author/Authors :
Shahabeddin, Masoumeh Department of Veterinary Surgery - Faculty of Veterinary Medicine - University of Tehran , Sharifi, Davood Department of Veterinary Surgery - Faculty of Veterinary Medicine - University of Tehran , Mokmeli, Soheila Canadian Optic & Laser (COL) center , Abarkar, Mohammad Islamic Azad University - Karaj branch , Shirani, Daryoush University of Tehran , Ghazaleh, Nooshin Department of Veterinary Surgery - Faculty of Veterinary Medicine - University of Tehran , Bahonar, Alireza University of Tehran
Pages :
6
From page :
35
To page :
40
Abstract :
Objectives-The aims of this study were evaluation the effects of blood laser irradiation on hemodynamic parameters, the amount of anesthetic drugs in maintenance of anesthesia and duration of recovery. Animals- Fifteen mixed breed dogs Procedures- dogs (25.0 ± 3.6 kg) were divided into three groups (n=5). The group I was acted as control and received only cold laser. The group II was premedicated with neuroleptanalgesics including Midazolam (0.2 mg/kg/iv/bw) plus Fentanyl (0.05 mg/kg/i.v/bw), and induction of anesthesia was done by Propofol (5 mg /kg/i.v/bw), then dogs were intubated for maintenance of anesthesia by Isoflurane 1% In addition to neuroleptanalgesics combined with Isoflurane, group III received Trans-cutaneous Blood Laser Irradiation ( Trans-cut BLI) through the cephalic venous line by a portable laser probe designed by Canadian optic &laser center immediately after intubation.The changes in cardiac rhythm, hemodynamic parameters including heart rate, blood pressure, SpO2 and the level of blood cortisol were measured before and after the induction of anesthesia on 5, 10 ,15,45, and 60 minutes. Results- No complication from anesthesia and blood laser radiation was noticed, and despite of some variation observed in collective data but there was no significant difference between homodynamic parameters, blood cortisol level, SpO2 and the doses of Isoflurane. However all of dogs in group III had smooth recovery and attained full conscious after end of anesthesia. Conclusions and clinical relevance- This study showed that transcutaneous blood laser irradiation is a safe method without any side effect to add anesthetic procedure.There was no deterioration effect on hemodynamic parameters and consumption amount of Isoflurane.
Farsi abstract :
ﻫﺪف- ﺑﺮرﺳﻲ اﺛﺮات ﺗﺎﺑﺶ ﻟﻴﺰر ﺟﻠﺪي ﺧﻮﻧﻲ ﺑﺮ ﭘﺎراﻣﺘﺮﻫﺎي ﻫﻤﻮدﻳﻨﺎﻣﻴﻜﻲ، ﻣﻴﺰان داروي ﻣﻮرد ﻧﻴﺎز ﺟﻬﺖ ﺣﻔﻆ ﺑﻴﻬﻮﺷﻲ و ﻣﺪت زﻣﺎن رﻳﻜﺎوري در ﺳﮕﻬﺎي ﺑﻴﻬﻮش ﻣﻲﺑﺎﺷﺪ. ﺣﻴﻮاﻧﺎت- ﭘﺎﻧﺰده ﻗﻼده ﺳﮓ ﻧﮋاد ﻣﺨﻠﻮط روش ﻛﺎر- ﺳﮓﻫﺎ ﺑﺼﻮرت ﺗﺼﺎدﻓﻲ ﺑﻪ ﺳﻪ ﮔﺮوه 5 ﺗﺎﻳﻲ ﺗﻘﺴﻴﻢ ﺷﺪﻧﺪ. در ﭘﻨﺞ ﺳﮓ ﮔﺮوه اول ﺗﻨﻬﺎ از ﺗﺎﺑﺶ ﻟﻴﺰر ﺳﺮد و در ﺳﮕﻬﺎي ﮔﺮوه دوم و ﺳﻮم ﺑﻌﻨﻮان ﭘﻴﺶ ﺑﻴﻬﻮﺷﻲ از داروي ﻣﻴﺪازوﻻم 0/5درﺻﺪ ﺑﺎ دوز 0/2 ﻣﻴﻠﻲ ﮔﺮم ﺑﻪ ازاي ﻫﺮ ﻛﻴﻠﻮﮔﺮم وﻓﻨﺘﺎﻧﻴﻞ ﺳﻴﺘﺮات ﺑﻪ ﻣﻘﺪار 0/05 ﻣﻴﻠﻲ ﮔﺮم ﺑﻪ ازاي ﻫﺮ ﻛﻴﻠﻮﮔﺮم اﺳﺘﻔﺎده ﺷﺪ. ﭘﺲ از اﻟﻘﺎي ﺑﻴﻬﻮﺷﻲ ﺑﺎ دوز 5 ﻣﻴﻠﻲ ﮔﺮم ﺑﻪ ازاي ﻫﺮ ﻛﻴﻠﻮﮔﺮم ﭘﺮوﭘﻮﻓﻮل ، ﺑﻤﻨﻈﻮر ﺗﺪاوم ﺑﻴﻬﻮﺷﻲ ازﻏﻠﻈﺖ ﻛﺎﻓﻲ اﻳﺰوﻓﻠﻮران ﺑﻪ ﻫﻤﺮاه اﻛﺴﻴﮋن اﺳﺘﻔﺎده ﮔﺮدﻳﺪ. در ﮔﺮوه ﺳﻪ ﭘﺲ از ﺗﺜﺒﻴﺖ وﺿﻌﻴﺖ ﺑﺎﻟﻴﻨﻲ ﺣﻴﻮان و رﺳﻴﺪن ﺑﻪ ﻋﻤﻖ ﺑﻴﻬﻮﺷﻲ ﻣﻨﺎﺳﺐ ﺗﺎﺑﺶ اﺷﻌﻪ ﻟﻴﺰر ﺧﻮﻧﻲ ﺟﻠﺪي ﺑﺎ ﭘﺮاب ﭘﻮرﺗﺎل)ﻗﺪرت=100 ﻣﻴﻠﻲ وات، ﻃﻮل ﻣﻮج=650 ﻧﺎﻧﻮﻣﺘﺮ، ﺳﻄﺢ 1 ﺳﺎﻧﺘﻲ ﻣﺘﺮ ﻣﺮﺑﻊ، زﻣﺎن= 20 دﻗﻴﻘﻪ( در ﻧﺎﺣﻴﻪ ﺳﺎﻋﺪ و ورﻳﺪ ﺳﻔﺎﻟﻴﻚ ﺑﻼﻓﺎﺻﻠﻪ ﭘﺲ از ﻟﻮﻟﻪ ﮔﺬاري ﻧﺎﻳﻲ اﻧﺠﺎم ﭘﺬﻳﺮﻓﺖ. در ﮔﺮوه دوم ﺗﻤﺎﻣﻲ ﻣﺮاﺣﻞ ﺑﻪ ﻏﻴﺮ از ﺗﺎﺑﺶ ﻟﻴﺰر ﺻﻮرت ﭘﺬﻳﺮﻓﺖ و ﺗﻤﺎﻣﻲ ﻓﺎﻛﺘﻮرﻫﺎي ﻣﺪ ﻧﻈﺮ ﺷﺎﻣﻞ ﺗﻌﺪاد ﺿﺮﺑﺎن ﻗﻠﺐ ، ﻓﺸﺎر ﺧﻮن، درﺻﺪ اﺷﺒﺎع ﺑﻮدن ﮔﻠﺒﻮﻟﻬﺎي ﻗﺮﻣﺰ از اﻛﺴﻴﮋن و ﺳﻄﺢ ﻛﻮرﺗﻴﺰول ﺧﻮن ﻗﺒﻞ و ﭘﺲ از ﺑﻴﻬﻮﺷﻲ در دﻗﺎﻳﻖ 5 ،10، 15، 45 و 60 دﻗﻴﻘﻪ ﺛﺒﺖ ﮔﺮدﻳﺪ. ﻧﺘﺎﻳﺞ- ﺑﻴﻬﻮﺷﻲ و ﻛﺎرﺑﺮد ﻟﻴﺰر ﺟﻠﺪي ﺧﻮﻧﻲ ﻫﻴﭽﮕﻮﻧﻪ ﻋﺎرﺿﻪ اي را در ﭘﻲ ﻧﺪاﺷﺘﻪ و ﻋﻼرﻏﻢ وﺟﻮد ﺗﻔﺎوﺗﻬﺎﻳﻲ در ﻳﺎﻓﺘﻪﻫﺎي ﺑﺪﺳﺖ آﻣﺪه ﻫﻴﭽﮕﻮﻧﻪ اﺧﺘﻼف ﻣﻌﻨﻲداري در ﭘﺎراﻣﺘﺮﻫﺎي ﻫﻤﻮدﻳﻨﺎﻣﻴﻜﻲ، درﺻﺪ اﺷﺒﺎع ﺑﻮدن ﮔﻠﺒﻮﻟﻬﺎي ﻗﺮﻣﺰ از اﻛﺴﻴﮋن، ﺳﻄﺢ ﻛﻮرﺗﻴﺰول ﺧﻮن و دوز ﻣﺼﺮﻓﻲ اﻳﺰوﻓﻠﻮران ﺑﻴﻦ ﮔﺮوهﻫﺎ ﻣﺸﺎﻫﺪه ﻧﮕﺮدﻳﺪ. ﻧﺘﻴﺠﻪ ﮔﻴﺮي و ﻛﺎرﺑﺮد ﺑﺎﻟﻴﻨﻲ- ﻛﺎرﺑﺮد ﻟﻴﺰر ﺣﻴﻦ ﺑﻴﻬﻮﺷﻲ ﻋﻼوه ﺑﺮ ارﺗﻘﺎء ﻛﻴﻔﻴﺖ ﻋﻤﻖ ﺑﻴﻬﻮﺷﻲ، زﻣﻴﻨﻪ ﻳﻚ رﻳﻜﺎوري آرام و ﻣﻨﺎﺳﺐ را ﻓﺮاﻫﻢ ﻣﻲآورد.
Keywords :
Transcutaneous blood laser irradiation , Anesthesia , Hemodynamic changes , Dog
Journal title :
Astroparticle Physics
Serial Year :
2013
Record number :
2446654
Link To Document :
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