Title of article
Immunophenotyping of Acute Leukemia in Northwestern Iran
Author/Authors
Asvadi Kermani, I Department of Hematology and Clinical Oncology - Shahid Ghazi Hospital, Tabriz University of Medical Sciences, Tabriz
Pages
3
From page
136
To page
138
Abstract
The significance of immunophenotyping is growing day by day. It
provides basic information in regard to classification and prognosis
of acute leukemia which helps the management of patients. This
study was conducted to Identify CD markers in leukemic patients
admitted to Tabriz, in northwestern Iran. Immunophenotyping of 60
patients with acute leukemia was determined. Patients with acute
myelogenous leukemia (AML) were 42% of M2 type, 23.6% M3,
15.7% M4, 13% M1 and 5.7% M5. CD13 and CD33 were the most
prevalent myeloid markers. T-lymphoid markers consisted mainly
of CD7 and its occurrence was mostly in M2 and M4, and least in M3
subtypes. The most common lymphoid markers in patients with Tcell
acute lymphoblastic leukemia (ALL) were CD2, CD3, CD7 and
in those with B-cell ALL were CD10, CD19 and HLA-DR. The most
prevalent myeloid markers in T-ALL were CD14, CD33 and CD13
Keywords
Immunophenotyping , acute leukemia , CD markers
Journal title
Astroparticle Physics
Serial Year
2002
Record number
2447162
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