Author/Authors :
Annamalai, Pandurangan Department of Pharmaceutical Technology, Meerut Institute of Engineering and Technology, Meerut-250002, India , Khosa, Ratan Lal Department of Pharmaceutical Technology, Meerut Institute of Engineering and Technology, Meerut-250002, India , Hemalatha, Siva Department of Pharmaceutics, Banaras Hindu University, Varanasi- 221005, India
Abstract :
In the present work, the antinociceptive action was assayed in several experimental models
in mice: writhing, formalin and hot plate tests. The crude alkaloid fraction (25, 50, 100 mg/
intraperitoneal injection (P < 0.001). In the formalin test, the extract (50 and 100 mg/kg) also
the extract (25, 50, 100 mg/kg) when given i.p. or pentazocine (5 mg/kg, s.c.) produced a
extract of Solanum trilobatum
peripherally.
