Title of article
Effect of Polymer Grade and Plasticizer Molecular Weights on Viscoelastic Behavior of Coating Solutions
Author/Authors
Honary, Soheila School of Pharmacy, Mazandaran University of Medical Sciences and Health Services, Sari , Golkar, Mohammadreza School of Chemical Engineering, Amir Kabir University,Tehran
Pages
3
From page
125
To page
127
Abstract
Film coating solutions containing different grades of HPMC (E5, E15 and E50) with and
without polyethylene glycol (with various molecular weights) were examined by an oscillatory
method, using Haake CV 100 rheometer. Fundamental rheological parameters (η, G and G″)
were measured over the frequency range from 0.04 to 2 Hz. The variation with frequency of the
loss tangent (a ratio of viscous to elastic contribution) provides a useful parameter for the
characterization of pharmaceutical products. Magnitudes of the loss tangent are discussed with
relation to coating solutions made by different grades of polymers and plasticizers
Keywords
Viscoelastic properties , Rheological parameters , Oscillatory method , Film coating
Journal title
Astroparticle Physics
Serial Year
2003
Record number
2447350
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