Title of article :
Antioxidant Activity of Otostegia persica (Labiatae) and its constituents
Author/Authors :
Shrififar, Fariba Department of Pharmacognosy, School of Pharmacy, Tehran University of Medical Sciences and Health Services, Tehran , Yass, Nargess Department of Pharmacognosy, School of Pharmacy, Tehran University of Medical Sciences and Health Services, Tehran , Shafiee, Abbas Department of Medicinal Chemistry, School of Pharmacy and Pharmaceutical Sciences Research Center, Tehran University of Medical Sciences and Health Services, Tehran
Abstract :
The antioxidant activity of the different extracts and fractions of aerial parts of Otostegia
persica (Burm.) Boiss. were evaluated using beta-carotene bleaching and lipid peroxidation
methods. The inhibitory activity of the plant extracts on the peroxidation of linoleic acid were
measured by ferric thiocyanate method in comparison to methanolic extracts of Green tee,
Ginkgo biloba, Vit.E and BHA as positive controls. Methanolic extract of the plant exhibited
strong antioxidant activity .Two compounds of methanolic extract which were separated by
column and paper chromatography showed significant antioxidant activity comparable to
butylated hydroxy anisole (BHA) and alpha tocopherol. These active compounds were identified
as morin and quercetin by using UV, IR, MS, ¹H and ¹³C NMR
Keywords :
Otostegia persica , Labiateae , Antioxidant activity , Lipid peroxidation , Free radicals , Morin , Quercetin
Journal title :
Astroparticle Physics
