Author/Authors :
Saei Ghare Naz, Marzieh Student Research Committee - Department of Midwifery and Reproductive Health - School of Nursing and Midwifery - Shahid Beheshti University of Medical Sciences, Tehran , Ramezani Tehrani, Fahimeh Reproductive Endocrinology Research Center - Research Institute for Endocrine Sciences - Shahid Beheshti University of Medical Sciences, Tehran , Alavi Majd, Hamid Department of Biostatistics - School of Allied Medical Sciences - Shahid Beheshti University of Medical Sciences, Tehran , Ahmadi, Fazlollah Department of Nursing - Faculty of Medical Sciences - Tarbiat Modares University, Tehran , Ozgoli, Giti Department of Midwifery and Reproductive Health - School of Nursing and Midwifery - Shahid Beheshti University of Medical Sciences, Tehran , Rashidi Fakari, Farzaneh Student Research Committee - Midwifery and Reproductive Health Research Center - Shahid Beheshti University of Medical Sciences, Tehran , Ghasemi, Vida Student Research Committee - Midwifery and Reproductive Health Research Center - Shahid Beheshti University of Medical Sciences, Tehran
Abstract :
Background: Polycystic ovarian syndrome is an endocrine disorder with many
complications. This syndrome is a growing concern among adolescents around the
world, with varying reports of its prevalence in different parts of the world.
Objective: This study aimed to determine the prevalence of polycystic ovary syndrome
in adolescents by a systematic review and meta-analysis.
Materials and Methods: In this study, a search for published articles with an English
language limitation and without a time limit was done in different databases (Scopus,
PubMed, and Web of Science, Emabse and Cochrane) in January 2019. The 12 studies
that met the criteria for entering a qualitative assessment scale of 5 and higher were
subjected to systematic review and meta-analysis. Egger and Begg’s tests were used
to check the publication bias. Data were analyzed with STATA software, version 11.1.
Results: Twelve studies were included for meta-analysis. The total number of
participants in the study was 149,477. The average quality score of all studies was 8.67 (range: 5–10). The prevalence of polycystic ovarian syndrome in adolescents based on the Rotterdam criteria was 11.04% (95% CI: 6.84–16.09%), based on the National Institute of Health criteria, it was 3.39% (95% CI: 0.28–9.54%), and based on Androgen Excess and Polycystic Ovary Syndrome Society, it was 8.03% (95% CI: 6.24–10.01%)
Conclusion: The result of this study showed that there is a variation in the prevalence
of PCOS in adolescents based on different criteria; we suggest more community-based
studies among adolescences in different parts of the world.
Keywords :
Polycystic ovary syndrome , Prevalence , Meta-analysis , Adolescence
