• Title of article

    Change in Oxygen Absorption of Human Adult and Fetal Hemoglobin Due to 940 MHz Electromagnetic Field Radiation Exposure

  • Author/Authors

    Banaei ، Aghdas - University of Tehran , Ghorchian ، Hedayatollah - IBB,University of Teahrn , Faraji Dana ، Reza - University of Tehran , ، Ali Akbar - University of Tehran

  • Pages
    9
  • From page
    187
  • To page
    195
  • Abstract
    The effects of electromagnetic fields (EMFs) radiation at the frequency of 940 MHz on the structure and function of human adult and fetal hemoglobin (HbA and HbF) were studied. After extraction and purification of HbA and HbF, the oxygen absorption values for exposed and unexposed HbA and HbF to EMF were compared. The slope of oxygen absorption curve for exposed HbA was increased while that for HbF was decreased compare to those before EMF exposing. Furthermore, the oxygen absorption saturation values were changed from 3.45.1 and from 5.13.1 mg l1, respectively for HbA and HbF after exposing to EMF. The UVVis, circular dichroism and fluorescence spectroscopy confirmed the quaternary structural changes of both proteins after EMF exposure. So that, the structural transition of HbA from tense to relaxed state caused an increasing in oxygen absorption whilst in HbF, transition from relaxed to tense state was occurred and therefore oxygen absorption was decreased.
  • Keywords
    Electromagnetic fields radiation , Fetal hemoglobin , Conformational changes , Structural transition
  • Journal title
    Biomacromolecular Journal
  • Serial Year
    2015
  • Journal title
    Biomacromolecular Journal
  • Record number

    2448865

    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=2448865