PVP- and PEG-grafted Ni Doped Iron Oxide Nanoparticles for Biomedical Applications: Electrochemical Synthesis and Characterization

Here, an electrochemical synthesis method is reported for the facile preparation of Ni doped iron oxide grafted with biocompatible polymers (i.e. PVP and PEG). PVP- and PEG coated Ni doped iron oxides (i.e. PVP-Ni-IOs and PEG-Ni-IOs) were fabricated through cathodic electrochemical deposition. The aqueous electrolyte containing 2.4 g Fe(NO3)3, 1g FeCl2, 0.2NiCl2 and 0.5 g PVP or 0.5 g PEG was used as the deposition media. The crystal structure, morphology, chemical composition, purity, and magnetite properties of the prepared PVP-Ni-IOs and PEG-Ni-IOs samples were scrutinized through XRD, FTIR, FESEM/ EDAX and VSM techniques. The presence of PVP and PEG on the surface of the IOs was confirmed via EDS and FTIR analyses. XRD and FE-SEM probes showed that the products are magnetite crystal structure with the particle size about 20 nm. EDAX results verified that the samples have metal ion doped Fe3O4 (about 7%Ni cations) composition. In addition, VSM measurement confirmed that the both PVP-Ni-IOs and PEG-Ni-IOs samples have superparamagnetic nature, showing the saturation magnetizations of 52.98 and 48.51 emu/g, respectively.