Title of article
Multicomponent Solvent-Free Synthesis, Antimicrobial and Antifungal Evaluation of Novel N-Amino Benzylthiolates
Author/Authors
Beyzaei, H Department of Chemistry - Faculty of Science - University of Zabol , Heidari, H Department of Chemistry - Faculty of Science - University of Zabol , Aryan, R Department of Chemistry - Faculty of Science - University of Zabol
Pages
9
From page
131
To page
139
Abstract
Novel N-amino benzylthiolates were synthesized via multicomponent reaction of malononitrile, isothiocyanates and benzyl halides
under conventional and solvent-free conditions. Various electron-donating and -withdrawing substitutes within both isothiocyanates and
benzyl halides were used to demonstrate the efficiency of new methodology. A broad spectrum of antibacterial and antifungal activities
were observed especially within benzyl halides containing electron-withdrawing aryl substituents.
Keywords
Multicomponent synthesis , Solvent-free condition , N-Amino benzylthiolate , Antibacterial activity , Antifungal property
Journal title
Astroparticle Physics
Serial Year
2018
Record number
2449734
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