Author/Authors :
Malekzadeh, Farideh Department of Epidemiology and Reproductive Health - Reproductive Epidemiology Research Center - Royan Institute for Reproductive Biomedicine - ACECR, Tehran , Moini, Ashraf Department of Endocrinology and Female Infertility - Reproductive Biomedicine Research Center - Royan Institute for Reproductive Biomedicine -ACECR, Tehran , Amirchaghmaghi, Elham Department of Endocrinology and Female Infertility - Reproductive Biomedicine Research Center - Royan Institute for Reproductive Biomedicine -ACECR, Tehran , Daliri, Leila Department of Epidemiology and Reproductive Health - Reproductive Epidemiology Research Center - Royan Institute for Reproductive Biomedicine - ACECR, Tehran , Akhoond, Mohammad Reza Department of Statistics - Mathematical Sciences and Computer Faculty - Shahid Chamran University of Ahvaz , Talebi, Mehrak Department of Endocrinology and Female Infertility - Reproductive Biomedicine Research Center - Royan Institute for Reproductive Biomedicine -ACECR, Tehran , Hosseini, Rihaneh Department of Gynaecology and Obstetrics - Arash Women’s Hospital - Tehran University of Medical Sciences
Abstract :
Background: Endometriosis is a common gynaecological disease that affects quality of life for women. Several studies
have revealed that both environmental and genetic factors contribute to the development of endometriosis. The aim
of this study was to investigate the distribution of ABO and Rh blood groups in Iranian women with endometriosis
who presented to two referral infertility centers in Tehran, Iran.
Materials and Methods: In this case-control study, women who referred to Royan Institute and Arash Women’s Hospital
for diagnostic laparoscopy between 2013 and 2014 were assessed. Based on the laparoscopy findings, we categorized
the women into two groups: endometriosis and control (women without endometriosis and normal pelvis). Chi-square
and logistic regression tests were used for data analysis.
Results: In this study, we assessed 433 women, of which 213 patients were assigned to the endometriosis group
while the remaining 220 subjects comprised the control group. The most frequent ABO blood group was O (40.6%).
The least frequent blood group was AB (4.8%). In terms of Rh blood group, Rh+ (90.1%) was more frequent than
Rh- (9.9%). There was no significant correlation between ABO (P=0.091) and Rh (P=0.55) blood groups and risk of
endometriosis. Also, there was no significant difference between the two groups with regards to the stage of endometriosis
and distribution of ABO and Rh blood groups (P>0.05).
Conclusion: Although the O blood group was less dominant in Iranian women with endometriosis, we observed no
significant correlation between the risk of endometriosis and the ABO and Rh blood groups. Endometriosis severity
was not correlated to any of these blood groups.
