Author/Authors :
Jabbarifakhar, M Department of Microbiology and Immunology - Faculty of Veterinary Medicine - University of Tehran , Mousavi, FS Department of Microbiology and Immunology - Faculty of Veterinary Medicine - University of Tehran , Ziafati, Z Department of Microbiology and Immunology - Faculty of Veterinary Medicine - University of Tehran , Rezaee, H Department of Microbiology and Immunology - Faculty of Veterinary Medicine - University of Tehran , Hosseini, H Department of Clinical Sciences - Faculty of Veterinary Medicine - Islamic Azad University - Karaj Branch, Alborz , Fallah, MH Razi Vaccine and Serum Research Institute - Agricultural Research and Extension Organization, Tehran , Esmaeelzadeh Dizaji, R Department of Avian Diseases - Faculty of Veterinary Medicine - University of Tehran , Ghalyanchilangeroudi, A Department of Microbiology and Immunology - Faculty of Veterinary Medicine - University of Tehran
Abstract :
Newcastle disease virus (NDV) is a prototype member of avian paramyxovirus serotype 1
(APMV-1), which causes severe and contagious disease in the commercial poultry and wild
birds. In this study, we report the results of phylogenetic analyses of recent NDVs isolated
from Markazi province of Iran during a recent outbreak in the commercial broiler with
respiratory signs and digestive system lesions. Phylogenetic analysis revealed that isolate was
clustered within class II NDV, in sub-genotype VII-g. This NDV isolates shared high
homology with the prevalent genotype NDV strains that circulate in China and Taiwan
(95.39%-84.89%). Overall, our results confirmed the presence of genotype VII-g in Iran
(The first report) and indicated that different genotypes of NDV could circulate
simultaneously among poultry (VII-d & VII-i). The phylogenetic characterization of these
isolates helps to characterize the evolution of NDV and may help with the development of
vaccines specific to our regional necessities.
Keywords :
Newcastle disease , Iran , Phylogenetic analysis , Genotyping , Genotype VII-g
