Title of article :
The Role of Urinary N-acetyl-beta-glucosaminidase in Diagnosis of Kidney Diseases
Author/Authors :
Mohkam, Masoumeh Pediatric Infection Research Center - Pediatric Nephrology Research Center Shahid Beheshti University of Medical Sciences - Tehran, Iran , Ghafari, Alireza MBA - Technical Deputy of Khanevade Hospital - Tehran, Iran
Abstract :
N-acetyl-beta-D-glucosaminidase (NAG) is a lysosomal enzyme present in the proximal convoluted tubules of the kidneys that may be used as a marker of proximal tubular damage and nephrotoxicity. An abnormal urinary NAG excretion has been reported in different kinds of renal disorders such as acute kidney injury, urinary tract infection, vesicoureteral reflux; diabetes mellitus; nephrotic syndrome; glomerulonephritis; hypertension; perinatal asphyxia; heavy metals poisoning; drug nephrotoxicity, renal allograft rejection; and heart failure. This paper provides an overview of the diagnostic value of urinary NAG in the nephrourology field.
Keywords :
Vesico-Ureteral Reflux , Pyelonephritis Hypertension , Kidney Diseases , Acute Kidney Injury , N-acetyl-beta-D-glucosaminidase
Journal title :
Astroparticle Physics
