Title of article :
Gold Nanoparticles/Cysteic Acid Modified Electrode for Simultaneous Electrochemical Determination of Tramadol and Paracetamol
Author/Authors :
Hassanvand, Zahra Department of Chemistry - Razi University, Kermanshah, Iran , Jalali, Fahimeh Department of Chemistry - Razi University, Kermanshah, Iran
Abstract :
Electrochemical deposition of gold nanoparticles (AuNPs) and l-cysteine on glassy carbon electrode was carried out to prepare a
modified electrode. The fabricated sensor showed good sensitivity and selectivity for simultaneous determination of paracetamol and
tramadol by square wave voltammetry. Linear ranges of 0.10-10.7 μM (paracetamol) and 0.50-63.6 μM (tramadol) were obtained with
detection limits of 0.03 and 0.17 μM, respectively. The proposed electrode was used successfully in the simultaneous determination of the
drugs in spiked human plasma samples.
Keywords :
Square wave voltammetry , Gold nanoparticles , Cysteic acid , Modified electrode , Paracetamol , Tramadol
Journal title :
Astroparticle Physics
