N-Methyl pyridinium p-toluene sulfonate (NMPyTs) catalyzed synthesis of pyrano[2,3-c]pyrazoles

A simple one pot synthesis of pyrano[ 2,3-c]pyrazoles was developed by a three component reaction of various benzaldehydes, malononitrile and 1-phenyl or hydro-3-methyl-1H-pyrazol-5(4H)-one in the presence of N-methyl pyridinium p-toluene sulfonate (NMPyTs) as catalyst. All of the synthesized compounds were identified by IR, ^1H NMR, ^13C NMR and mass spectroscopy. In the mentioned method, the use of thermal condition is avoided. The key advantages of this process are high yields, shorter reaction times, easy work-up, and purification of products by non-chromatographic method. The synthesis of pyrano[2,3-c] pyrazoles using NMPyTs as an efficient catalyst is the novel methodology work.