Comparison of 25-hydroxyvitamin D and Calcium Levels between Preeclampsia and Normal Pregnant Women and Birth Outcomes

Introduction The main aim of this study was to compare serum level of 25 hydroxyl vitamin D [25(OH) D] between women with preeclsia and normal individuals and birth outcomes. Material and Methods This cross sectional study was conducted on 650 normal primigravida women in their first 24–28 weeks of pregnancy. After 3 months of followup, serum levels of 25(OH) D and calcium were measured in 38 preeclsia women (case) and in 38 normal pregnant (control).  In addition, APGAR scores and newborn parameters were evaluated in infants of two groups. Results Preeclsia was shown in about 5.84% (38 women) of pregnancies. Comparison of 25(OH) D levels between two main groups showed no significant differences (P 0.05).  Also, the calcium level was lower in preeclsia women than the normal women (P 0.05). The results revealed a significant correlation between neonatal two groups with regards to gestational age, birth weight, birth length, head circumference and Apgar score in the first minute of birth. Conclusion Although the difference of 25(OH) D levels between preeclsia and healthy wom­en is not significant, lower levels of serum calcium were associated with preeclsia. Also, the newborn parameters improved in the neonates of the control group in comparison to those of the preeclsia group. This difference might have resulted from mothers’ different health statuses.