An electrochemical acetaminophen sensor based on La^3+/Co3O4 nanoflowers modified graphite screen printed electrode architecture

In this study, the La^3+/Co3O4 nanoflowers were synthesized by co-precipitation method. The morphology of the La^3+/Co3O4NFs were characterized using scanning electron microscopy (SEM), and were further used to modify the graphite screen printed electrode (GSPE). The electrochemical behavior of acetaminophen at La3+/Co3O4NFs/GSPE has been studied in aqueous solutions. Experimental results showed that the La3+/ Co3O4NFs modified GSPE possess excellent electrocatalytic activity toward the detection of acetaminophen. Under optimum conditions, the La^3+/Co3O4NFs modified electrode exhibited high sensitivity and stability to acetaminophen over a wide linear range of concentrations from 0.5μM to 250.0μM, with a detection limit of 0.09μM. Finally, the proposed sensor was successfully applied to the detection of acetaminophen in real samples.