Author/Authors :
Mahyar, Abolfazl Associate Professor of Pediatrics - Department of Pediatrics - Qazvin Children Hospital - Qazvin University of Medical Sciences, Qazvin , Ayazi, Parviz Associate Professor of Pediatrics - Department of Pediatrics - Qazvin Children Hospital - Qazvin University of Medical Sciences, Qazvin , Abbasi, Marjan Pediatrician, Department of Pediatrics - Qazvin Children Hospita - Qazvin University of Medical Sciences, Qazvin , Dalirani, Reza Associate Professor of Pediatrics - Mofid Children Hospital - Shahid Beheshti University of Medical Sciences, Tehran , Taremiha, Alireza Specialist of Pediatric Infectious Diseases, Department of Pediatrics - Qazvin Children Hospital - Qazvin University of Medical Sciences, Qazvin , Javadi, Amir Biostatistician - Qazvin University of Medical Sciences, Qazvin , Esmaeily, Shiva MSc in Statistics - Qazvin University of Medical Sciences, Qazvin
Abstract :
Background: According to some reports, 25-hydroxy vitamin D (25 (OH) D) deficiency leads to respiratory diseases. Given the high prevalence of acute bronchiolitis in
young infants, the assessment of 25 (OH) D status is very important for this disease.
Objectives: This study was conducted to determine the relationship between the serum levels of 25 (OH) D and acute bronchiolitis in young infants.
Methods: In the present study, 57 patients with acute bronchiolitis (case control) were compared with 57 healthy children (control group) in terms of 25 (OH) D serum
levels. The serum levels of 25 (OH) D were measured using the ELISA method. The results were analyzed and compared between the two groups.
Results: The mean and standard deviation of 25 (OH) D serum levels were 26 9.5 and 23.3 8.3 ng/mL in the case and control groups, respectively. No significant
difference was observed between the two groups in terms of 25 (OH) D serum levels (P = 0.11).
Conclusions: This study showed that there is no significant difference between children with acute bronchiolitis and normal children in terms of serum 25 (OH)Dlevels.
It therefore seems that 25 (OH) D does not play any role in the pathogenesis of acute bronchiolitis. Further studies in this area are recommended.
