Title of article :
Management of Fungal Keratitis in Pediatric Patients
Author/Authors :
Badiee, Parisa Professor Alborzi Clinical Microbiology Research Center - Shiraz University of Medical Sciences, Shiraz , Nejabat, Mahmood Ophthalmology Department - Khalili Hospital - Shiraz University of Medical Sciences , Choopanizadeh, Maral Professor Alborzi Clinical Microbiology Research Center - Shiraz University of Medical Sciences, Shiraz
Abstract :
Context: Fungal keratitis is an uncommon infection with high morbidity in pediatric patients. Trauma is the most common risk
factor for infection in children. Thus, rapid diagnosis should be made by scoring clinical features and mycological examination.
This review discusses the management of fungal keratitis in pediatric patients.
Evidence Acquisition: In this narrative review, the most recently published dataonpediatric fungal keratitis, respective prominent
signs and symptoms, etiologic agents, diagnosis and treatment of this infection have been reviewed.
Results: Laboratory methodssuch as investigation of smear by potassium hydroxideandstainingandculturalandmolecular methods
can be helpful in the diagnosis. Treatment of this infection with improved outcome is challenging. Medical therapy (topical and
systemic treatments) is the first choice of treatment, but early surgical intervention and removal of the infected tissues are critical
for effective cure. Lack of response to these therapies requires corneal transplantation. Unfortunately, loss of useful vision rate was
found in patients even with treatment by antifungal agents.
Conclusions: The signsandsymptomsof fungal keratitis are similar to those of other microbial keratitis. Use of diagnosticmethods
and early treatment are helpful for recovery in infected pediatric patients.
Keywords :
Fungi , Cornea , Keratitis , Pediatric Patients , Aspergillus , Fusarium
Journal title :
Astroparticle Physics