Synthesis and Characterization of γ-Fe2O3@HAp@β-CD Core-Shell Nanoparticles As a Novel Magnetic Nanoreactor and Its Application in the One-Pot Preparation of β-azido Alcohols, β-nitro Alcohols, and β-cyanohydrins

In this study, β-cyclodextrin(β-CD) supported, hydroxyapatite encapsulated γ-Fe2O3 (γ-Fe2O3@HAp@β-CD) was successfully prepared and evaluated as a solid–liquid phase transfer catalyst and also a molecular host system and nanoreactor for the nucleophilic ring opening of epoxides in water for the preparation of β-azido alcohols, β-nitro alcohols, and β-cyanohydrins. The catalyst was characterized with FT-IR, XRD, TGA and SEM. This procedure offers several advantages including excellent regioselectivity, high yields, short reaction times, recyclable catalyst, easy separation of the catalyst through external magnet, and easy work-up