Author/Authors :
Salehinejad, Jahanshah Department of Oral and Maxillofacial Pathology - Dental Research - School of Dentistry - Mashhad University of Medical Sciences, Mashhad , Sahebnasagh, Zahra Department of Oral Maxillofacial Radiology - School of Dentistry - Zahedan University of Medical Sciences, Zahedan , Saghafi, Shadi Departments of Oral Maxillofacial Pathology - Mashhad University of Medical Sciences, Mashhad , Sahebnasagh, Zoha Departments of Oral Maxillofacial Radiology - Mashhad University of Medical Sciences, Mashhad , Amiri, Nafise Departments of - Nanotechnology Research Center, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad
Abstract :
Intraoral ancient schwannoma is a rare type of oral schwannoma, which is encapsulated and well
demarcated from the surrounding tissues. Ancient schwannomas are associated with conventional
features of neurilemmoma; however, they are distinguished from other types of schwannoma due
to factors such as the long history, cellular architecture showing hypocellularity, and hyalinized
matrices. This systematic review was performed through searching in databases such as PubMed and
Google Scholar using related keywords (intraoral, oral, ancient, schwannoma, and neurilemmoma).
Eventually, 26 case reports were systematically reviewed by the researchers. Required data were
extracted by one researcher, and all the selected articles were reviewed in full text after screening.
This systematic review aimed to determine the most significant influential factors in intraoral ancient
schwannoma and evaluate the diagnostic and therapeutic methods in this regard.