An Overview on Fluoroquinolone Drugs for the Treatment of Tubercular Infection

The fluoroquinolones-levofloxacin, moxifloxacin and gatifloxacin have potent bactericidal activities against Mycobacterium tuberculosis. They have the potential activity in managing both drug-susceptible and drug-resistant tuberculosis as well as the possibility of shortening the period of therapy. The emergence of drug-resistance, fluoroquinolone-resistant, multidrugresistant and extensively drug-resistant tuberculosis created a challenge to control the tuberculosis globally. The newer fluoroquinolones have clinical efficacy in some of the patients. So, the utility of newfluoroquinolone drugs for the treatment of tuberculosis is needed.