Author/Authors :
Nikpour, Maryam Student Research Committee - Health Research Institute - Babol University of Medical Sciences, Babol, Iran , Tirgar, Aram Social Determinants of Health Research Center - Health Research Institute - Babol University of Medical Sciences, Babol, Iran , Hajiahmadi, Mahmod Non Communicable Pediatric Diseases Research Center - Health Research Institute - Babol University of Medical Sciences, Babol, Iran , Ebadi, Abbas Behavioral Sciences Research Center - Life style institute - Nursing Faculty - Baqiyatallah University of Medical Sciences, Tehran, Iran , Ghaffari, Fatemeh Nursing Care Research Center - Health Research Institute - Babol University of Medical Sciences, Babol, Iran , Hosseini, Akram Clinical Research Development Center - Shahid Beheshti Hospital - Health Research Institute -Babol University of Medical Sciences, Babol, Iran , Heidari, Behzad Mobility Impairment Research Center - Health Research Institute - Babol University of Medical Sciences, Babol, Iran
Abstract :
Background: Among the inflammatory factors, high-sensitivity C-reactive protein (hs-
CRP) is one of the strongest predictors of cardiovascular disease. This study aimed to
evaluate the relationship of serum hs-CRP level with shift work among reproductive age
women.
Methods: This cross-sectional study was conducted from September 2017 to May 2018 in
three cities in Mazandaran Province, North of Iran. Through purposive sampling, 350
women (172 shift workers and 178 day workers) were recruited. The guideline
recommended by the American Heart Association and the Centers for Disease Control and
Prevention was used to interpret the result of hs-CRP measurement as the following: less
than 1 μg/ml: low CVD risk; 1–3 μg/ml: moderate CVD risk; and more than 3 μg/ml: high
CVD risk. The data were analyzed using the independent-sample t and the chi-square tests
as well as the logistic regression analysis.
Results: 11.1% of participants had a serum hs-CRP level of more than 3 μg/ml. This rate
among shift workers was significantly greater than day workers (15.6% vs. 7.0%;
p=0.012). After adjusting the effects of potential confounders shift work significantly
increased the odds of serum hs-CRP level of more than 3 μg/ml by 2.45 times (OR=2.45,
95% CI: 1.01–5.93, p=0.047).
Conclusion: Shift work is a significant predictor of high serum hs-CRP level probably due
to its association with sleep problems and occupational stress. Improving the knowledge of
female shift workers about the importance of quality sleep can reduce their CVD risk and
improve their health
Keywords :
Shift work , Reproductive age , High-sensitivity C-Reactive Protein , Cardiovascular disease , Women Citation
