Title of article :
Studying a specific tumor marker by a new method and analyzing its efficiency in labeling animals
Author/Authors :
Navabpour, Mojtaba Department of Radiation Technology - Faculty of Paramedical Sciences - Shahid Beheshti University of Medical Sciences, Tehran, Iran , Jamshidinia, Zhila Department of Radiation Technology - Faculty of Paramedical Sciences - Shahid Beheshti University of Medical Sciences, Tehran, Iran , Bakhshandeh, Mohsen Department of Biology - Science and Research Branch - Islamic Azad University, Tehran, Iran
Abstract :
Purpose: To recognize affective factors in delivering X-ray contrast agents (which have high atomic number) via gallium carrier to liver or lymphatic neoplasm cells.
Materials and Methods: Since uptake of gallium by liver has been reported in numerous researches, it was bonded with a contrast media (metrizoate). X-ray imaging was done to determine geometric features of liver. Results: Radiographic image was obtained. Maximum contrast in radiographic image was observed 72 hours after injection. In addition, increase of effective tumor atomic number caused by metrizoate helped the tumor to be treated by a smart radiotherapy method (i.e. photoelectron therapy). It increased photoelectron therapy efficiency up to two thousand percentages. Conclusion: A new method of killing cancer cells can be developed using contrast agents. Also, metrizoate-labeled gallium is recommended for marking animals.
Keywords :
Pharmaceutical carriers , gallium , metrizoate complex , tumor location , tumor mapping
Journal title :
Astroparticle Physics
