Title of article
Promising role for Gc-MAF in cancer immunotherapy: from bench to bedside
Author/Authors
Saburi, Ehsan Department of Molecular Medicine - Zanjan University of Medical Sciences, Zanjan, Iran , Saburi, Amin Chemical Injuries Research Center - Baqiyatallah University of Medical Sciences, Tehran, Iran , Ghanei, Mostafa Chemical Injuries Research Center - Baqiyatallah University of Medical Sciences, Tehran, Iran
Pages
11
From page
228
To page
238
Abstract
Immunotherapy has been used for years in many types of cancer therapy. Recently, cancer immunotherapy has focused on mechanisms which can enhance the development of cell-mediated immunity. Anticancer medications are administered to inhibit immunosuppressive factors such as nagalase enzyme, which is produced by neoplastic cells and destroys macrophage activating factor (Gc-MAF). Anti-neoplastics medications can also enhance immune-cell activity against tumors. Such medications show great potential in cancer immunotherapy using natural human mechanisms against neoplasms.
Keywords
Vitamin D , Gc-MAF , Macrophage activating factor , Cancer , Immunotherapy
Journal title
Astroparticle Physics
Serial Year
2017
Record number
2471854
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