Author/Authors :
Saburi, Ehsan Department of Molecular Medicine - Zanjan University of Medical Sciences, Zanjan, Iran , Saburi, Amin Chemical Injuries Research Center - Baqiyatallah University of Medical Sciences, Tehran, Iran , Ghanei, Mostafa Chemical Injuries Research Center - Baqiyatallah University of Medical Sciences, Tehran, Iran
Abstract :
Immunotherapy has been used for years in many types of cancer therapy. Recently, cancer immunotherapy has focused on mechanisms which can enhance the development of cell-mediated immunity. Anticancer medications are administered to inhibit immunosuppressive factors such as nagalase enzyme, which is produced by neoplastic cells and destroys macrophage activating factor (Gc-MAF). Anti-neoplastics medications can also enhance immune-cell activity against tumors. Such medications show great potential in cancer immunotherapy using natural human mechanisms against neoplasms.
Keywords :
Vitamin D , Gc-MAF , Macrophage activating factor , Cancer , Immunotherapy
