Author/Authors :
Verma, Kavita Department of Conservative Dentistry and Endodontics - Saraswati Dental College and Hospital, India , Bains, Rhythm Department of Conservative Dentistry and Endodontics - Faculty of Dental Sciences - King George’s Medical University, India , Kumar Bains, Vivek Department of Periodontology - Saraswati Dental College and Hospital, India , Rawtiya, Manjusha People’s College of Dental Sciences and Research Centre - Bhopal - Madhya Pradesh, India , Loomba, Kapil Department of Conservative Dentistry and Endodontics - Career Postgraduate Institute of Dental Sciences and Hospital - Lucknow - Uttar Pradesh, India , Charan Srivastava, Shrish Department of Orthodontics and Dentofacial Orthopedics - Saraswati Dental College and Hospital, India
Abstract :
The purpose of this review is to gain an overview of the applications of the dental pulp stem
cells (DPSCs) in the treatment of various medical diseases. Stem cells have the capacity to
differentiate and regenerate into various tissues. DPSCs are the adult stem cells that reside in
the cell rich zone of the dental pulp. These are the multipotent cells that can be explained by
their embryonic origin from the neural crest. Owing to this multipotency, these DPSCs can be
used in both dental and medical applications. A review of literature has been performed using
electronic and hand-searching methods for the medical applications of DPSCs. On the basis
of the available information, DPSCs appear to be a promising alternative for the regeneration
of tissues and treatment of various diseases, although, long-term clinical trials and studies are
needed to confirm their efficacy.
Keywords :
Alzheimer’s disease , dental pulp stem cells , myocardial infarction , neurogenic differentiation , tissue differentiation
