Title of article
Extramedullary Manifestation of Multiple Myeloma in the Oral Cavity
Author/Authors
Hansen, Cristiano de Assis Pereira Former Medical Resident in Clinical Oncology - A.C.Camargo Cancer Center, São Paulo, Brazil , Schmidt Filho, Jayr Hematologist - A.C.Camargo Cancer Center, São Paulo, Brazil , Nascimento, Marina de Mattos Hematologist - A.C.Camargo Cancer Center, São Paulo, Brazil , Abreu Alves, Fábio Chief of Dental Surgery Department - A.C.Camargo Cancer Center, São Paulo, Brazil
Pages
2
From page
611
To page
612
Abstract
Background: Extramedullary plasmacytomas occurs in about 20% of multiple myeloma (MM) recurrences. Extramedullary disease seems to respond poorly to thalidomide and has adverse prognostic implication. When disease recurs in the oral cavity with soft tissue infiltration, some authors defend upfront surgical excision prior to radiotherapy with the aim of achieving better local control. We describe herein such an atypical case of recurrence from MM, with complete local response after 2 cycles of chemotherapy. Unfortunately, disease progressed later on, and the patient died after 9 months post-recurrence. This emphasizes the prognostic impact of extramedullary disease manifestation in MM.
Keywords
Multiple myeloma , Oral cavity , Recurrences
Journal title
Astroparticle Physics
Serial Year
2018
Record number
2474356
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