Author/Authors :
Sayyedan, Fatemeh Sadat Department of Materials Engineering - Biomaterials Research Group - Isfahan University of Technology, Isfahan , Fathi, Mohammad hossein Department of Materials Engineering - Biomaterials Research Group - Isfahan University of Technology, Isfahan , Edris, Hossein Department of Materials Engineering - Biomaterials Research Group - Isfahan University of Technology, Isfahan , Doostmohammadi, Ali Department of Materials Engineering - Shahrekord University, Shahrekord , Mortazavi, Vajihesadat Department Operative Dentistry - School of Dentistry - Isfahan University of Medical Sciences, Isfahan , Shirani, Farzaneh Department Operative Dentistry - School of Dentistry - Isfahan University of Medical Sciences, Isfahan
Abstract :
Background: The most important limitation of glass ionomer cements (GICs) is the weak
mechanical properties. Our previous research showed that higher mechanical properties could be
achieved by addition of forsterite (Mg2SiO4) nanoparticles to ceramic part of GIC. The objective
of the present study was to fabricate a glass ionomer- Mg2SiO4 nanocomposite and to evaluate the
effect of addition of Mg2SiO4 nanoparticles on bioactivity and fluoride release behavior of prepared
nanocomposite.
Materials and Methods: Forsterite nanoparticles were made by sol-gel process. X-ray diffraction
(XRD) technique was used in order to phase structure characterization and determination of
grain size of Mg2SiO4 nanopowder. Nanocomposite was fabricated via adding 3wt.% of Mg2SiO4
nanoparticles to ceramic part of commercial GIC (Fuji II GC). Fluoride ion release and bioactivity of
nanocomposite were measured using the artificial saliva and simulated body fluid (SBF), respectively.
Bioactivity of specimens was investigated by Fourier transitioned-infrared spectroscopy (FTIR), scanning
electronmicroscopy (SEM), Inductively Coupled Plasma Optical Emission Spectroscopy (ICP-OES)
and registration of the changes in pH of soaking solution at the soaking period. Statistical analysis was
carried out by one Way analysis of variance and differences were considered significant if P < 0.05.
Results: The results of XRD analysis confirmed that nanocrystalline and pure Mg2SiO4 powder
was obtained. Fluoride ion release evaluation showed that the values of released fluoride ions
from nanocomposite are somewhat less than Fuji II GC. SEM images, pH changes of the SBF and
results of the ICP-OES and FTIR tests confirmed the bioactivity of the nanocomposite. Statistical
analysis showed that the differences between the results of all groups were significant (P < 0.05).
Conclusion: Glass ionomer- Mg2SiO4 nanocomposite could be a good candidate for dentistry and
orthopedic applications, through of desirable fluoride ion release and bioactivity.
Keywords :
Bioactivity , fluoride release , forsterite nanoparticles , glass ionomer cement , sol-gel
