• Title of article

    Evaluation of the Effective Electrospinning Parameters Controlling Kefiran Nanofibers Diameter Using Modelling Artificial Neural Networks

  • Author/Authors

    Esnaashari ، Sara - Tehran University of Medical Sciences , Naghibzadeh ، Majid - Shahid Sadoughi University of Medical Sciences , Adabi ، Mahdi - Tehran University of Medical Sciences , Faridi-Majidi ، Reza - Tehran University of Medical Sciences

  • Pages
    11
  • From page
    239
  • To page
    249
  • Abstract
    Objective(s): This paper investigates the validity of Artificial Neural Networks (ANN) model in the prediction of electrospun kefiran nanofibers diameter using 4 effective parameters involved in electrospinning process. Polymer concentration, applied voltage, flow rate and nozzle to collector distance were used as variable parameters to design various sets of electrospinning experiments for production of electrospun kefiran nanofibers. Methods: The Scanning Electron Microscopy (SEM) was used to investigate the morphology and evaluate the size of the nanofiber. Data set was drawn using k fold cross-validation method, which was the most suitable scheme for the volume of the data in this work. Data were partitioned into the five series and trained and tested via ANN method. Results: The Scanning Electron Microscopy (SEM) images of the generated nanofiber samples were confirmed that all of the samples were fine and defectfree. Our results indicated that the network including four input variables, three hidden layers with 10, 18 and 9 nodes in each layer, respectively, and one output layer obtained the highest efficiency in the testing set. The mean squared error (MSE) and linear regression (R) between observed and predicted nanofibers diameter were 0.0452 and 0.950, respectively. Conclusions: The results demonstrated that the proposed neural network was appropriately performed in assessing the input parameters and prediction of nanofibers diameter.
  • Keywords
    Kefiran , Nanofibers , Electrospinning , ANN , modeling
  • Journal title
    Nanomedicine Research Journal
  • Serial Year
    2017
  • Journal title
    Nanomedicine Research Journal
  • Record number

    2478675