Author/Authors :
Yerebasmaz, Neslihan Department of Obstetrics and Gynecology - Ankara Etlik Zubeyde Hanim Women's Health Teaching and Research Hospital, Ankara, Turkey , Kutlu, Ali Department of Allergy and Immunology - GATA Haydarpasa Teaching Hospital, Istanbul, Turkey , Aydin, Ersin Department of Dermatovenereology - Kasimpasa Military Hospital, Istanbul, Turkey , Karabacak, Ercan Department of Dermatovenereology - GATA Haydarpasa Teaching Hospital, Istanbul, Turkey , Öztürk, Sami Department of Allergy and Immunology - GATA Haydarpasa Teaching Hospital, Istanbul, Turkey , Gun, Ismet Department of Obstetrics and Gynecology - GATA Haydarpasa Teaching Hospital, Istanbul, Turkey
Abstract :
Progesterone hypersensitivity (PH) is a rare clinical condition that displays
hypersensitivity to endogenous or exogenous progesterone. It is characterized by cyclic
dermatologic manifestations at the end of the luteal phase that disappear some days after
menses. We present a case of 24-year-old woman showing severe angioedema attacks
occurring from the first day of her menstruation and continuing for 4-5 days and having
positive progesterone intradermal test (IDT). To our knowledge, there is no case in the
literature which is coupled with PH isolated angioedema attacks. In this case report we will
discuss diagnostic value of progesterone IDT.
Keywords :
Angioedema , Intradermal test , Premenstrual syndrome , Progesterone hypersensitivity
