Title of article
Discordant tooth agenesis and peg-shaped in a pair of monozygotic twins: Clinical and molecular study
Author/Authors
Azeredo Alves Antunes, Lívia Department of Specific Formation - School of Dentistry - Fluminense Federal University - Nova Friburgo, Brazil , Calvano Küchler, Erika Unit of Clinical Research - Fluminense Federal University - Niterói, Brazil , de Castro Costa, Marcelo Department of Pediatric Dentistry and Orthodontics - School of Dentistry - Federal University of Rio de Janeiro - Rio de Janeiro, Brazil , Santos Antunes, Leonardo Department of Specific Formation - School of Dentistry - Fluminense Federal University - Nova Friburgo, Brazil , Mauro Granjeiro, José National Institute of Metrology - Quality and Technology - Head of Bioengineering Program - and Head of Cell Therapy Center - Unit of Clinical Research - Fluminense Federal University - all in Rio de Janeiro, Brazil
Pages
5
From page
820
To page
824
Abstract
The present report aimed to study an uncommon case of a pair of twins that presented a discordant
dental phenotype. Family investigation, clinical, radiographic examination and molecular analysis were
performed in both girls. Molecular analysis confirmed the monozygosity by deoxyribonucleic acid
chip technology. One twin presented tooth agenesis in left upper lateral incisor and peg-shaped
on the contra lateral side while the other twin had no dental alterations. The dental casts study
employed digital caliper to compare morphological dimensions and showed alteration only in
peg-shaped tooth. In conclusion, this study provide support that one or more mutated gene could
cause discordances in dental phenotype in these monozygotic twins.
Keywords
Dental anomalies , dental development , monozygotic twins , tooth agenesis
Journal title
Astroparticle Physics
Serial Year
2013
Record number
2479361
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