Lichen planus pemphigoides: A case report

Lichen planus pemphigoides (LPP) is a rare autoimmune blistering disease that is characterized by the development of vesico-bullous skin lesions in patients with lichen planus. The histopathology of LPP reveals a sub_epidermal blister with linear deposition of IgG and /or C3 along the dermal_epidermal junction (DEJ) upon direct immunofluorescence (DIF). We hereunder describe a case of lichen planus pemphigoides in a 69-year-old otherwise healthy male who initially presented with typical lesions of lichen planus (LP), predominantly on the lower extremities; then, bullous lesions developed on the normal skin.