Title of article :
Effect of Short-Term Maximal Exercise on Biochemical Markers of Muscle Damage, Total Antioxidant Status, and Homocysteine Levels in Football Players
Author/Authors :
Hammouda, Omar Research Laboratory ‘’Sport Performance Optimisation’’ - National Center of Medicine and Science in Sport , Chtourou, Hamdi Research Laboratory ‘’Sport Performance Optimisation’’ - National Center of Medicine and Science in Sport , Chaouachi, Anis Research Laboratory ‘’Sport Performance Optimisation’’ - National Center of Medicine and Science in Sport , Chahed, Henda Laboratory of Biochemistry - CHU Farhat Hached, Sousse, Tunisia , Ferchichi, Salyma Laboratory of Biochemistry - CHU Farhat Hached, Sousse, Tunisia , Kallel, Choumous Laboratory of hematology - CHU Habib Bourguiba, Sfax, Tunisia , Chamari, Karim Research Laboratory ‘’Sport Performance Optimisation’’ - National Center of Medicine and Science in Sport , Souissi, Nizar Research Laboratory ‘’Sport Performance Optimisation’’ - National Center of Medicine and Science in Sport
Abstract :
Purpose: Prolonged physical exercise results in transient elevations of
biochemical markers of muscular damage. This study examined the effect of
short-term maximal exercise on these markers, homocysteine levels (Hcy), and
total antioxidant status (TAS) in trained subjects.
Methods: Eighteen male football players participated in this study. Blood
samples were collected 5-min before and 3-min after a 30-s Wingate test.
Results: The results indicated that plasma biochemical markers of muscle
injury increased significantly after the Wingate test (P<0.05). Moreover,
significant increase of white blood Cells and their main subpopulations (i.e.
monocytes, neutrophiles, and lymphocytes) (P<0.001) has been observed.
Likewise, uric acid, total bilirubin, and TAS increased significantly after
exercise (P<0.05). However, Hcy levels were unaffected by the Wingate test (for
3-min post-exercise measurement).
Conclusions: Short-term maximal exercise (e.g. 30-s Wingate test) is of
sufficient intensity and duration to increase markers of muscle damage, and
TAS; but not Hcy levels. Increases in the selected enzymes probably come
primarily from muscle damage, rather than liver damage. Moreover, increase
of TAS confirms the Wingate test induced oxidative stress.
Keywords :
Wingate Test , Antioxidants , Homocysteine , Exercise , Injury , Muscles
Journal title :
Astroparticle Physics
