• Title of article

    Relationship of blood groups to pemphigus: Do blood group antigens have a biological role? A Case-control study

  • Author/Authors

    Bakhtiari, Sedigheh Oral Medicine Department - Dental School - Shahid Beheshti University of Medical Sciences, Tehran , Toossi, Parviz Dermatology Department - Medical School - Shahid Beheshti University of Medical Sciences, Tehran , Taheri, Jamileh Beigom Oral Medicine Department - Dental School - Shahid Beheshti University of Medical Sciences, Tehran , Azimi, Somayyeh International Research Collaborative Oral Health and Equity - Department of Anatomy - Physiology and Human Biology - School of Human Sciences - University of Western Australia, Australia , Kalantari Bengar, Mahnaz Dental School - Shahid Beheshti University of Medical Sciences, Tehran , Namazi, Zahra Tehran University of Medical Sciences, Tehran , Rafieian, Nasrin Dietary Supplements and Probiotic Research Center - Alborz University of Medical Sciences, Karaj

  • Pages
    4
  • From page
    75
  • To page
    78
  • Abstract
    Background: ABO blood group antigens may play a role in the pathophysiology of certain diseases. Several studies have investigated the relation between blood group and autoimmune disorders. In this research, we evaluated the associations between ABO blood types and rhesus (Rh) factor in pemphigus patients. Methods: In this case-control, hospital-based study, we evaluated the prevalence of blood group on 110 pemphigus patients and 126 controls. The chi-square test was used to compare qualitative variables and examine the relationship between blood groups and Rh in pemphigus patients and a control group. Results: Blood group (O) was found in 46.3% (O+ 38.2%) of patients with pemphigus, followed by blood type A (30.0%; A+ 27.3%), and blood groups B and AB. Compared to the control group, we noted that the distribution of blood groups, with Rh (P=0.73) or without Rh (P=0.52), did not significantly differ. Conclusion: Although some associations between blood group antigens and specific diseases have been reported in the literature, this study did not find any statistically significant relationship between blood groups and pemphigus disease.
  • Keywords
    pemphigus , blood group antigens , Rh-Hr blood group system
  • Journal title
    Astroparticle Physics
  • Serial Year
    2017
  • Record number

    2480592