Author/Authors :
ZHUSSUPOV, Baurzhan Columbia University Global Health Research Center of Central Asia, Almaty, Kazakhstan , HERMOSILLA, Sabrina Columbia University in the City of New York, New York City, United States of America , TERLIKBAYEVA, Assel Columbia University Global Health Research Center of Central Asia, Almaty, Kazakhstan , AIFAH, Angela Columbia University in the City of New York, New York City, United States of America , MA, Xin Columbia University in the City of New York, New York City, United States of America , ZHUMADILOV, Zhaxybay Center for Life Sciences Nazarbayev University, Astana, Kazakhstan , ABILDAYEV, Tleukhan National Center for TB in Kazakhstan, Almaty, Kazakhstan , DARISHEVA, Meruyert Columbia University Global Health Research Center of Central Asia, Almaty, Kazakhstan , BERIKKHANOVA, Kulzhan Center for Life Sciences Nazarbayev University, Astana, Kazakhstan
Abstract :
Background: This study examined the association between incident pulmonary tuberculosis (TB) and social and be-havioral characteristics in Almaty Oblast, Kazakhstan from 2012 to 2013.
Methods: We used a matched case-control design to estimate the role of factors for acquiring pulmonary TB. Totally 324 individuals were recruited from Sep 2012 to Mar 2013. Participants included 110 TB index cases with newly de-tected pulmonary TB. Each case was matched with one household and one community control. A total of 107 house-hold and 107 community controls were included to the study. Adjusted odds ratios measuring associations between TB and risk factors were calculated by using a conditional multiple logistic regression analysis.
Results: TB cases were more likely to be younger, recent smokers and have diabetes, when compared to household controls. Between TB cases and community controls, TB was significantly associated with age, non-married family status, living in a rented home, recent smoker, and having diabetes. Comparing TB cases with community controls, we found that foreign birth was marginally associated with incident TB case status.
Conclusion: Our findings confirm the role of modifiable risk factors for TB in Kazakhstan; highlighting the im-portance of developing interventions addressing social determinants and proximate risk factors for high TB burden regions.
