Title of article
Hypoglycemic Activity of Casearia esculenta Roxb. in Normal and Diabetic Albino Rats
Author/Authors
Arula, Balasubramanian Department of Pharmaceutics - Vinayaka Mission’s College of Pharmacy, India , Kothai, Ramalingam Department of Pharmaceutics - Vinayaka Mission’s College of Pharmacy, India , Christina, Arokiasamy Josephine Maria bK. M. College of Pharmacy, India
Pages
5
From page
47
To page
51
Abstract
The hypoglycemic effect of ethanolic extract of Casearia esculenta was investigated on alloxan induced diabetic rats. The blood glucose levels were measured at 0, 1, 2 and 3 h after the treatment. The ethanolic extract of C. esculenta (250 mg/kg) reduced the blood glucose of normal rat from 85.50±1.22 to 64.67±3.27 mg/dl, 3 h after oral administration of the extract (P<0.05). It also significantly lowered blood glucose level in alloxan induced diabetic rat from 331.67±4.90 to 130.33±6.53 mg/dl, 3 h after oral administration of the extract (P<0.05). The antihyperglycemic activity of C. esculenta was compared with tolbutamide, an oral hypoglycemic agent.
Keywords
C. esculenta , Antihyperglycemic , Hypoglycemic , alloxan
Journal title
Astroparticle Physics
Serial Year
2006
Record number
2481210
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