Author/Authors :
Jalalpure, Sunil S. Department of Pharmaceutical Chemistry - KLES’s College of Pharmacy, India , Alagawadi, Kallanagoda R. Department of Pharmaceutical Chemistry - KLES’s College of Pharmacy, India , Mahajanshetty, Channabasappa S. Department of Pharmaceutical Chemistry - KLES’s College of Pharmacy, India , Salahuddin, Mahmad Department of Pharmacognosy and Phytochemistry - KLES’s College of Pharmacy, India , Shah, Biren Department of Pharmacognosy and Phytochemistry - KLES’s College of Pharmacy, India
Abstract :
Seed oils of Passiflora edulis, Jatropa curucas, Tinospora cordifolia, Sesbania grandiflora and Sapindus laurifolia were investigated for their antihelmintic property against Pheritima pasthuma. Three concentrations (10, 50 and 100 mg/ml) of each oil were studied in the bioassay, which involved the determination of time of paralysis and time of death of the worm. Sesbania grandiflora showed the highly significant antihelmintic activity in both the parameters (paralysis and death), while Tinospora cordifolia showed significant effect in case of time of death. Piperazine citrate (10 mg/ml) was included in the assay as standard reference drug.
Keywords :
Antihelmintic , Pheritima pasthuma , Seed oils , Piperazine citrate
