Author/Authors :
mosavian, azam Department of Exercise Physiology - Kish International Camps -Tehran University, Kish Island, Iran , nori, reza Department of Exercise Physiology - Kish International Camps -Tehran University, Kish Island, Iran , gaeini, abbas ali Department of Exercise Physiology - Faculty of Sport Sciences - Tehran University, Tehran, Iran , hemmatinafar, mohammad Department of Exercise Physiology - Faculty of Sport Sciences - Tehran University, Tehran, Iran
Abstract :
Introduction: The objective of the present research was to determine the effect of
low-intensity eccentric training with blood flow restriction (BFR) on Hepatocyte
Growth Factor (HGF) and myogenic factor 5 (Myf5), in non-athletes young men.
Methods: In this study, 20 non-athlete young men were allocated to two eccentric
training and eccentric training with BFR groups. Eccentric training program includes
75 knee extension repetitions in severity of 30% IRM within three sets by using
isokinetic device. BFR was made by using air pressure meter and a muscular biopsy
was taken from the vastus lateralis muscle of active leg, 48 hours before and 24 hours
after the training program. The data were analyzed using independent and paired ttests.
Results: The results of analysis showed that HGF serum levels and mRNA Myf5
expression in both eccentric resistance training and without BFR groups had a
significant increase compared to pre-test levels (P≤0.05). Moreover, it was observed
that HGF serum levels and mRNA Myf5 expression in training group with BFR had a
significant increase of 6.39% and 4.05%, respectively, compared to training group
without BFR (P≤0.05).
Conclusion: The results of this research showed that eccentric training with and
without BFR may improve the activation and proliferation indicators of satellite cells.
But, in spite of this matter, it seems that eccentric resistance training with BFR may
have a more significant effect on activation and reproduction of satellite cells.
