Title of article :
Prevalence of CYP2C19 Genetic Polymorphism among Normal People and Patients with Hepatic Diseases
Author/Authors :
Hashemizadeh, Z. Prof. Alborzi Clinical Microbiology Research Center-Shiraz University of Medical Sciences, Shiraz , Malek-Hosseini, S. A. Transplant Research Center- Shiraz University of Medical Sciences, Shiraz , Badiee, P. Prof. Alborzi Clinical Microbiology Research Center-Shiraz University of Medical Sciences, Shiraz
Abstract :
The distribution of geno type frequencies in Iranian healthy people and patients
with various hepatic diseases was not significantly different. This may allow the physicians to predict a
tailoring dose regimens based on the individual’s metabolic capacity, decrease the risk of harmful side
effects of the drugs, and optimize the treatment.
Keywords :
Cytochrome P450 , CYP2C19 , Hepatic disorders , Liver transplantation
Journal title :
Astroparticle Physics
