Author/Authors :
Kazeminezhad, Behrang Department of Pathology - Shahid Modarres Educational Hospital - Shahid Beheshti University of Medical Sciences, Tehran, IR Iran , Gharib, Atoosa Department of Pathology - Shahid Modarres Educational Hospital - Shahid Beheshti University of Medical Sciences, Tehran, IR Iran , Asadi, Zahra Department of Pathology - Shahid Modarres Educational Hospital - Shahid Beheshti University of Medical Sciences, Tehran, IR Iran
Abstract :
Introduction: Primary renallymphoma(PRL) is rare while secondary involvement of the kidney bylymphomais not infrequent. All
morphologic varieties of lymphomacan involve kidney. The mostcommonreported PRL is large B cell lymphoma. To our knowledge
no prior case of primary renal mantle cell lymphoma (MCL), pleomorphic variant, has been reported.
Case Presentation: A 67-year-old male presented with right flank pain. On examination a right sided abdominal mass and a unilateral
varicocele were detected. Onimaging studies there was a large mass of right kidney without nodal or other organs involvement.
Heunderwent right nephrectomy. Ongross pathological evaluation, a deformed kidney which was almost totally involved by tumor
with hemorrhagic nodular cut surfaces was identified. Histologic evaluation and immunohistochemistry (IHC) staining followed
by fluorescence in situ hybridization (FISH) study for t (11; 14) (q 13; q 32) / CCND1 - IGH confirmed diagnosis of MCL, pleomorphic type.
Finally the patient was admitted in another hospital for continuing the treatment and received chemotherapy there. After one year
of initial diagnosis the patient is still alive.
Conclusion: The aim of this manuscript was to highlight a possible presentation of primary MCL, pleomorphic variant.
