The Effect of Glutamine Supplementation on Delayed Onset Muscle Soreness and Skin Temperature in Untrained Elderly Male People with Type 2 Diabetes

Objective: Effect of resistance training on muscle mass increase, blood glucose control, hemoglobin (HbA1c) reduction, on type 2 diabetes (T2DM), has been approved. While injuries and delayed onset muscle soreness (DOMS) may lead to some difficulties in diabetic patients to continue training exercise. The purpose of this study was to investigate the effect of glutamine supplementation (o.1 g / 1kg / each day for 4 weeks) on DOMS, creatine kinase (CK) contraction and the skin temperature of the elbow flexing muscles in the untrained T2DM patients. Materials and Methods: The research was an experimental study. This study was a double blinded randomized controlled trial. Subjects were randomly assigned into 4 groups of diabetic glutamine (N=10), diabetic placebo of Maltodextrin (N=10), healthy glutamine (N=10) and healthy placebo of Maltodextrin (N=10). Variables were measured before, 24, 48 and 72 Hours after exercise. Data were analyzed by ANOVA and Bonferroni's post hoc test in SPSS-18 software. Results: Glutamine was effective on changes in CK and pain sensation 72 hours after exercise in diabetics. (P-value: 0.0001).In skin temperature was not significant different. Conclusion: Glutamine was not effective in preventing and reducing DOMS, but it may reduce the DOMS period.