Author/Authors :
Souri, Effat Department of Medicinal Chemistry - Tehran University of Medical Sciences, Tehran , Amin, Gholamreza Department of Pharmacognosy - Faculty of Pharmacy and Pharmaceutical Sciences Research Center - Tehran University of Medical Sciences, Tehran , Farsam, Hassan Department of Medicinal Chemistry - Tehran University of Medical Sciences, Tehran , Jalalizadeh, Hassan Department of Medicinal Chemistry - Tehran University of Medical Sciences, Tehran , Barezi, Saba Department of Medicinal Chemistry - Tehran University of Medical Sciences, Tehran
Abstract :
Antioxidants are vital substances which possess the ability to protect the body from damage caused by free radical induced oxidative stress. A variety of free radical scavenging antioxidants exist within the body which many of them are derived from dietary sources like fruits, vegetables and teas. In this study the antioxidant activity and radical scavenging activity of methanolic extracts of selected plant materials, traditionally used by Iranian population as folk remedies was evaluated against linoleic acid peroxidation and 2,2-diphenyl-1-picrylhydrazyl radical. The antioxidant activity expressed as IC50 ranged from1.28 ng/ml in Biebresteinia multifida to 63.48 ng/ml in Polypodium vulgare. Radical scavenging activities expressed as IC50 varied from 1.83 µg/ml in Salix sp. to 187.88 µg/ml in Allium hirtifolium.
Keywords :
Antioxidant , Free radical , Linoleic acid , Medicinal plant , Radical scavenging , DPPH