Title of article
Endometriosis Classification and The Role of Tumor Necrosis Factor-Alpha Polymorphisms as A Therapeutic Target
Author/Authors
Barra ، Fabio Academic Unit of Obstetrics and Gynecology - IRCCS Ospedale Policlinico San Martino , Desideri ، Lorenzo Ferro Academic Unit of Obstetrics and Gynecology - IRCCS Ospedale Policlinico San Martino , Maggiore ، Umberto Leone Roberti Academic Unit of Obstetrics and Gynecology - IRCCS Ospedale Policlinico San Martino , Vellone ، Valerio Gaetano Department of Surgical and Diagnostic Sciences - IRCCS Ospedale Policlinico San Martino , Maramai ، Mattia Academic Unit of Obstetrics and Gynecology - IRCCS Ospedale Policlinico San Martino , Scala ، Carolina Academic Unit of Obstetrics and Gynecology - IRCCS Ospedale Policlinico San Martino , Ferrero ، Simone Academic Unit of Obstetrics and Gynecology - IRCCS Ospedale Policlinico San Martino
Pages
2
From page
76
To page
77
Abstract
In the recent original research published on International Journal of Fertility and Sterility the association between tumor necrosis factor-alpha (TNF-α) genetic polymorphisms and endometriosis in 150 Iranian patients suffered this disease. The authors notably found a lower frequency of TNF-α -863C/A allele A among the affected patients in comparison with healthy women, although this difference was not significant by adjusting multiple testing. We deem that the authors should specify, if these patients had peritoneal nodules, ovarian endometrioma/deep infiltrating endometriosis (DIE) nodules or combination of them, since it has been hypothesized that these phenotypes may represent three distinct pathogenetic entities of endometriosis.
Keywords
Endometriosis , Genetic Polymorphisms , Tumor Necrosis Factor , Alpha
Journal title
International Journal of Fertility and Sterility
Serial Year
2020
Journal title
International Journal of Fertility and Sterility
Record number
2483696
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