Author/Authors :
Quang Hanh, Tran Department of Obstetrics - Nghe An Obstetrics and Pediatrics Hospital - Nghe An, Vietnam , Van Du, Vu Department of Treatment on Demand - National Hospital of Obstetrics and Gynecology - Hanoi, Vietnam , Thu Hien, Pham Department of Treatment on Demand - National Hospital of Pediatrics - Hanoi, Vietnam , Dinh Chinh, Duong Department of Neurology - Nghe An Friendship General Hospital - Nghe An, Vietnam , Ba Loi, Cao Department of Science and Training - National Institute of Malaria Parasitology and Entomology - Hanoi, Vietnam , Manh Dung, Nguyen Department of Anesthesiology and Critical Care - 108 Military Centre Hospital - Hanoi, Vietnam , Ngoc Anh, Do Department of Medical Parasitology - Military Medical University - Hanoi, Vietnam , Thi Kieu Anh, Tran Department of Paediatric - Vinh Medical University - Nghe An, Vietnam
Abstract :
Background and Objectives: Identification of GBS serotypes provides helpful information for appropriate the development
of suitable vaccines; however, no reports from Vietnam have been published. This study has been performed to find
the prevalence and serotypes of group B Streptococcus isolated from vagina of pregnant women in Nghe An province,
Vietnam.
Materials and Methods: Vaginal swabs were collected from pregnant women at 35-37 weeks of gestation at the Nghe An
Obstetrics and Pediatrics Hospital, Vietnam between May 2018 and July 2019. The swabs were cultured on 5% sheep blood
agar for isolation of GBS. All isolates were identified using the Gram staining, CAMP test and specific PCR. GBS strains
were serotyped using the multiplex PCR assays.
Results: The prevalence of vaginal GBS colonization was 9.20% of 750 participants. Among the isolates, serotypes III
(39.13%) and V (31.89%) were the most frequent, followed by serotypes Ia (11.59%), VI (11.59%), Ib (2.90%), II (1.45%)
and VII (1.45%), respectively. Serotypes IV, VIII and IX were not found.
Conclusion: The prevalence of GBS in the Nghe An province of central Vietnam was similar to reports from other parts of
the world. The predominat GBS serotypes (III, V, Ia and VI) were slightly different from those previously described from
other regions around the world. The high frequency of serotype VI was a notable feature of the strains from pregnant women
in Vietnam.
Keywords :
Group B Streptococcus , Prevalence , Serotypes , Nghe An , Vietnam
