Author/Authors :
Tobaldini Russo, Flávia Instituto Brasileiro de Controle do Câncer (IBCC) - São Paulo, Brazil , Cristina Martins de Almeida Macedo, Maria Instituto Brasileiro de Controle do Câncer (IBCC) - São Paulo, Brazil , Amoedo Fernades, Pedro Instituto Brasileiro de Controle do Câncer (IBCC) - São Paulo, Brazil , Yukari Okada, Larissa Instituto Brasileiro de Controle do Câncer (IBCC) - São Paulo, Brazil , Augusto Monetta da Silva, Lucas Faculdade de Ciências Médicas Santa Casa de São Paulo - São Paulo, Brazil , Menin Simões, Camila Instituto Brasileiro de Controle do Câncer (IBCC) - São Paulo, Brazil , Neves Cavalcante, Jamilla Instituto Brasileiro de Controle do Câncer (IBCC) - São Paulo, Brazil , de Almeida Simões, Aline Instituto Brasileiro de Controle do Câncer (IBCC) - São Paulo, Brazil , de Souza Sampaio Almeida, Manuella Instituto Brasileiro de Controle do Câncer (IBCC) - São Paulo, Brazil , Almeida Viol Ferreira Lopes, Maricy Instituto Brasileiro de Controle do Câncer (IBCC) - São Paulo, Brazil , Luiz da Silva, Roberto Instituto Brasileiro de Controle do Câncer (IBCC) - São Paulo, Brazil
Abstract :
Acute Lymphoblastic Leukemia is a very aggressive malignant disorder of lymphoid cells in adults, with recurrence (30 to 60% of the cases) after the initial treatment. Until this moment, there is no gold standard therapy for the treatment of adult patients with acute relapsed/refractory lymphoblastic leukemia. In this case report, we describe two cases of relapsed leukemia: one of lymphocytic leukemia B and one of trilineage leukemia, which presented a satisfactory response to treatment with Bortezomib associated with Vincristine, Dexamethasone, and Bendamustine.
