Author/Authors :
Samsami, Alamtaj Infertility Research Center - Department of Obstetrics and Gynecology - School of Medicine - Shiraz University of Medical Sciences - Shiraz, Iran , Davoodi, sara Infertility Research Center - Department of Obstetrics and Gynecology - School of Medicine - Shiraz University of Medical Sciences - Shiraz, Iran , Ghasmpour, Leila Infertility Research Center - Department of Obstetrics and Gynecology - School of Medicine - Shiraz University of Medical Sciences - Shiraz, Iran , Moradi Alamdarloo, Shaghayegh Infertility Research Center - Department of Obstetrics and Gynecology - School of Medicine - Shiraz University of Medical Sciences - Shiraz, Iran , Rahmati, Jamshid School of Medicine - Shiraz University of Medical Sciences - Shiraz, Iran , Karimian, Ali School of Medicine - Shiraz University of Medical Sciences - Shiraz, Iran
Abstract :
Resistant ovary syndrome (ROS) is a presentation of
hypergonadotrophic hypogonadism condition with very low
incidence. Infertility is one of the most common complaints of
women with this syndrome. We herein present a case of a 27-yearold
woman with all features of secondary amenorrhea and
secondary sexual characteristics. In 2018, the patient was referred
to the Hazret-e-Zeinab Infertility Center affiliated to Shiraz
University of Medical Sciences, Shiraz, Iran. She was diagnosed
with secondary amenorrhea and increased gonadotropin secretion
after menopause. However, the patient had a normal antral follicle
count, anti-Müllerian hormone level, 46, XX karyotype, and
thyroid function. After taking oral contraceptives her menstruation
started, but she showed no response to high doses of exogenous
gonadotropins. She was advised to have an embryo derived from
in vitro maturation. By using patients’ own oocyte maturation, this
technique could be a better treatment for infertile women with
ROS. This case report is particularly interesting due to the rarity of
its prevalence and similarity with primary ovarian insufficiency.
