Title of article
BK Virus-Associated Hemorrhagic Cystitis in Children Suffering from Malignancies: Report of Three Cases
Author/Authors
Ansari, Shahla Department of Hematology-Oncology - Ali Asghar Children’s Hospital - Iran University of Medical Sciences, Tehran , Ashayeri, Neda Department of Hematology-Oncology - Ali Asghar Children’s Hospital - Iran University of Medical Sciences, Tehran
Pages
3
From page
33
To page
35
Abstract
BK virus-associated hemorrhagic cystitis (HC) is frequent in patients
undergoing bone marrow transplantation, but it rarely occurs among
other immunosuppressed patients particularly in those who are receiving
chemotherapy for hematologic malignancies. Herein, we report three children
with malignancies suffering from hemorrhagic cystitis due to BK virus
infection who were successfully improved.
Early detection of BK virus using RT-PCR technique was undertaken. With
administration of antiviral agents; specifically, IVIG or leflunomide, BK
virus-associated HC could be successfully managed in children affected by
malignancies and consequently, chemotherapy of underlying disorder might be
continued after virus elimination.
Keywords
BK virus , Cystitis hemorrhagic , Leflunomide , Immunosuppression
Journal title
Astroparticle Physics
Serial Year
2019
Record number
2487706
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