Author/Authors :
JEBA SUNILSON, ANBU Masterskill College of Nursing and Health - School of Pharmacy , MOHAN, SYAM Masterskill College of Nursing and Health - School of Pharmacy , ALI MOHAMED, MUSTAFA University of Malaya - Faculty of medicine , THOMAS, JOHN Masterskill College of Nursing and Health - School of Pharmacy , GNANA KUMARI, ANITA M.S. University - Centre for Marine Institute
Abstract :
The aim of this study was to evaluate antitumour activity of the roots of Hibiscus tiliaceus Linn. against Dalton’s Ascitic Lymphoma (DAL) in Swiss albino mice. A significant enhancement of mean survival time (MST) of H. tiliaceus treated tumour bearing mice was found with respect to control group. H. tiliaceus treatment was found to enhance peritoneal cell counts. When these H. tiliaceus treated animals underwent intraperitoneal (i.p.) inoculation with DAL cells, tumour cell growth was found to be inhibited. The results indicated that, H. tiliaceus treated group were able to reverse the haematological parameters, protein and Packed Cell Volume (PCV) consequent to tumour inoculation with in fourteen days after the transplantation.
